Organic Syntheses Seminar: Exploring New Methodologies to Enhance Synthetic Efficiency
Seminar | March 14 | 11 a.m.-12 p.m. | Pitzer Auditorium, 120 Latimer Hall
Discovery of new synthetic methodologies not only prompts diverse synthesis of natural and designed functional molecules, but also leads to more efficient synthesis (step-economical and cost-effective) of known compounds with important functions. In this lecture I will summarize our recent results on methodology development, which include preparation of spiro-fused indolines via intramolecular oxidative coupling and its application in the total synthesis of indoline alkaloids, organocatalytic Michael addition with functionalized nitroolefins and its application in the preparation of anti-flu drugs; and copper-catalyzed arylation of nucleophiles with aryl chlorides under relatively mild conditions.
Light refreshments served at The Coffee Lab at 10:50am.