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Tuesday, May 23, 2017

The Role of Astrocytes in Neurovascular Coupling at the Capillary and Arteriole Level in the Retina and Brain

Seminar: Oxyopia Seminar | May 23 | 12-1:30 p.m. | 489 Minor Hall

Anusha Mishra, University College London, UK

Neuroscience Institute, Helen Wills

Neuronal activity evokes a spatially and temporally localized increase in blood flow to power the information processing carried out by the neurons, a phenomenon that underlies BOLD fMRI signals. This neurovascular coupling occurs both in the brain and the retina.

In the retina, both light- and glial-stimulation evoke pronounced arteriole dilations (30.8±3.7% and 23.5±4.1%, respectively). This...   More >