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BioE Seminar: “Directed evolution for synthetic biology applications”

Seminar | October 16 | 12-1 p.m. | 106 Stanley Hall

Andrew Ellington, The University of Texas at Austin

Bioengineering (BioE)

Fall 2013 Seminar Series

Wednesday, October 16
12noon - 1:00pm
106 Stanley Hall, UC Berkeley

“Directed evolution for synthetic biology applications”

Andrew Ellington
Wilson and Kathryn Fraser Research Professorship in Biochemistry
The University of Texas at Austin

One of the prevailing notions in the nascent field of synthetic biology is that parts, circuits, and systems that have otherwise been optimized by billions of years of evolution are completely fungible. We have developed methods for the facile evolutionary engineering of enzymes, pathways, and organisms, and will show examples of how novel transcription networks, genetic codes, and organismal consortia can be built using directed evolution. That said, directed evolution is just a waystation to rational design, and progress on computational prediction of macromolecular structure and function will be considered as part of the synthetic biology toolset.