Organic Syntheses Seminar: Exploring New Methodologies to Enhance Synthetic Efficiency

Seminar | March 14 | 11 a.m.-12 p.m. |  Pitzer Auditorium, 120 Latimer Hall

 Prof. Dawei Ma, State Key Laboratory of Bio-Organic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry

 College of Chemistry

Discovery of new synthetic methodologies not only prompts diverse synthesis of natural and designed functional molecules, but also leads to more efficient synthesis (step-economical and cost-effective) of known compounds with important functions. In this lecture I will summarize our recent results on methodology development, which include preparation of spiro-fused indolines via intramolecular oxidative coupling and its application in the total synthesis of indoline alkaloids, organocatalytic Michael addition with functionalized nitroolefins and its application in the preparation of anti-flu drugs; and copper-catalyzed arylation of nucleophiles with aryl chlorides under relatively mild conditions.

 Light refreshments served at The Coffee Lab at 10:50am., 510-643-0572