The neural circuits underlying motor planning and short-term memory

Seminar | September 24 | 4-5 p.m. | 125 Li Ka Shing Center

 Karel Svoboda, Janelia Research Campus, HHMI

 Neuroscience Institute, Helen Wills

Our goal is to uncover the principles by which mammalian neural circuits perform fundamental computations, from perception to action. Cortex is parcellated into areas with distinct functions, each of which contains complex local circuits. Cortical areas in turn associate into mesoscale circuits with other cortical and subcortical areas via long-range connections. Information is represented by action potentials in widely distributed ensembles of neurons. What are the mechanisms shaping neural representations, and how do the representations drive behavior? We use molecular, optical, electrophysiological, and computational methods to address these questions in behaving mice in the context of motor planning and short-term memory.