Mitotic checkpoint regulators in genome stability and insulin signaling

Seminar | October 28 | 4-5 p.m. | 106 Stanley Hall

 Hongtao Yu, The University of Texas Southwestern Medical Center

 College of Chemistry

The spindle checkpoint ensures the fidelity of chromosome segregation during mitosis and guards against aneuploidy. Several checkpoint proteins have a moonlighting function to control insulin signaling in interphase. Recent studies on the crosstalk between the cell division module and insulin signaling will be discussed.