Merck-Banyu Lecture in Organic Chemistry: Synthesis of Pillar-Shaped Macrocyclic Compounds “Pillar[n]arenes” Providing Supramolecular Assemblies
Seminar | October 24 | 11 a.m.-12 p.m. | 120 Latimer Hall
Macrocyclic compounds play a major role in supramolecular chemistry because of their beautiful shape, nano-scale size and molecular recognition ability. Numerous supramolecular architectures have been constructed and studied as new components of materials as well as entities related to biological structural formation and functions using various macrocyclic hosts.
In 2008, we reported a new class of macrocyclic hosts named pillar[n]arenes.[1,2] Linear 1,2-dichloroethane and bulky chlorocyclohexane acted as template solvents for high-yield synthesis of pillar- and pillararenes, respectively. They have unique symmetrical pillar structures due to their para-bridge linkage. We have synthesized various topological and functional molecules based on functionality of pillar[n]arenes, and constructed 2D sheets and 3D vesicles based on geometric assemblies of their pentagonal and hexagonal structures.
 Ogoshi, T.; Kanai, S.; Fujinami, S.; Yamagishi, T.; Nakamoto, Y. J. Am. Chem. Soc. 2008, 130, 50225023.
 Reviews and book: Ogoshi, T.; Yamagishi, T.; Nakamoto, Y. Chem. Rev. 2016, 116, 79378002; Murray, J.; Kim, K.; Ogoshi, T.; Yao. W.; Gibb. B. C. Chem. Soc. Rev. 2017, in press; Kakuta, T.; Yamagishi, T.; Ogoshi, T. Chem. Commun. 2017, in press; Ogoshi, T.; Yamagishi, T. Chem. Commun. 2014, 50, 4776-4787; Pillararenes, Ogoshi, T. Ed.; The Royal Society of Chemistry: Cambridge, 2016.
 Ogoshi, T.; Sueto, R.; Yoshikoshi, K.; Yasuhara, K.; Yamagishi, J. Am. Chem. Soc. 2016, 138, 80648067; Ogoshi, T.; Takashima, S.; Yamagishi, T. J. Am. Chem. Soc. 2015, 137, 1096210964; Ogoshi, T.; Yoshikoshi, K.; Sueto, R.; Nishihara, H.; Yamagishi, T. Angew. Chem. Int. Ed. 2015, 54, 64666469; Ogoshi, T.; Shimada, Y.; Sakata, Y.; Akine, S.; Yamagishi, T. J. Am. Chem. Soc. 2017, 139, 56645667.; Ogoshi, T.; Sueto, R.; Yoshikoshi, K.; Sakata, Y.; Akine, S.*; Yamagishi T. Angew. Chem. Int. Ed. 2015, 54, 98499852.
Light refreshments will be served at 10:50 at The Coffee Lab