RSS FeedUpcoming EventsSkin Deep: Stem Cells at the Nexus of the Niche, Physiology, and the External Environment, March 20https://events.berkeley.edu/mcb/event/208548-divisions-of-biochemistry-biophysics-andThe Hsu laboratory seeks to understand how tissue formation, regeneration, and repair are shaped by diverse stimuli at the level of the niche, physiology, and the external environment. The lab primarily focuses on the mammalian skin—an accessible organ with diverse cell types and multiple populations of somatic stem cells, but takes a multidisciplinary approach that blends stem cell biology with neurobiology, genetics, and physiology. In the seminar, I will share our findings on (1) how neuronal activities and hormonal changes modulate regeneration and repair, particularly when organisms experience stressful events, and (2) how to regenerate fully functional skin with diverse cell types after injury.
Division(s): Divisions of Biochemistry, Biophysics & Structural Biology, Division of Cell Biology, Development & Physiology, and Genetics, Genomics, Evolution & Development
https://events.berkeley.edu/mcb/event/208548-divisions-of-biochemistry-biophysics-and
Developing the Toolkit for Investigating Multi-Organelles’ Interactome in Live Cells, March 20https://events.berkeley.edu/mcb/event/243474-developing-the-toolkit-for-investigatingAbstract: My presentation will highlight three recent breakthroughs in imaging, sensing, and modulating organelles’ interactome in live cells. Firstly, we address speed and throughput challenges by using a universal lipid-specific dye for ratiometric imaging of membrane-associated organelles, enabling segmentation of up to 15 structures. Secondly, we explore lanthanide-doped nanoparticles capable of up-converting infrared photons into intense visible light at the nanoscale, facilitating diverse bio-applications, including the tracking of single-molecule transport, super-resolution microscopy, nanoscale thermometry, and nanoscale optical tweezers. Lastly, we introduce nanoscale capacitive optoelectrodes for in vivo neuromodulation, offering high-efficiency optical neuromodulation with minimal side effects. These advancements enable super-resolution imaging, sensing, and modulation of single molecules and live cells in their physiological environment, providing insights into the nanoscale world inside living cells.
Bio: Dayong Jin is a distinguished professor at University of Technology Sydney, an ARC Laureate Fellow, Fellow of Australian Academy of Technology and Engineering, and a Clarivate Highly Cited Researcher, with expertise covering biomedical engineering, nanotechnology, microscopy, microfluidics, and analytical chemistry, to enable rapid detection, imaging and sensing of cells and molecules. He established the UTS Institute for Biomedical Materials & Devices (IBMD) to transform advances in phonics and materials into disruptive biotechnologies.
Division(s): INFORMAL SEMINAR
https://events.berkeley.edu/mcb/event/243474-developing-the-toolkit-for-investigating
Neuroscience Student Seminar Series Seminar, March 21https://events.berkeley.edu/mcb/event/209803-neuroscience-student-seminar-series-seminarDivision(s): Neuroscience Student Seminar Serieshttps://events.berkeley.edu/mcb/event/209803-neuroscience-student-seminar-series-seminarSpeakers: Ben Engel (Biozentrum, University of Basel, Switzerland): Talk Title to be Announced; Christopher Obara (Janelia Research Campus): Talk Title to be Announced; Bronwyn A. Lucas (MCB and Center for Computational Biology, UC Berkeley): Visualizi..., March 25https://events.berkeley.edu/mcb/event/237720-speakers-ben-engel-biozentrum-university-of-basel17th Annual CDP Spring Symposium: Cell Biology at the Nanoscale
This seminar is partially sponsored by NIH
Division(s): Division of Cell Biology, Development & Physiology
https://events.berkeley.edu/mcb/event/237720-speakers-ben-engel-biozentrum-university-of-basel
MCB Postdocs Research Showcase, March 28https://events.berkeley.edu/mcb/event/243456-mcb-postdocs-research-showcase

Featuring talks and posters from current MCB Postdocs, keynote speaker Christopher Barnes (Stanford), a career panel, a postdoc/faculty lunch and evening postdoc social mixer.

https://events.berkeley.edu/mcb/event/243456-mcb-postdocs-research-showcase
RNA Editing: Innate Immunity and Autoinflammatory Disease, April 1https://events.berkeley.edu/mcb/event/243473-rna-editing-innate-immunity-and-autoinflammatoryAdenosine-to-Inosine (A-to-I) RNA editing, catalyzed by ADAR enzymes, is prevalent in metazoans. Previous research, including our own, has revealed that the primary function of RNA editing by ADAR1 is to ensure sufficient editing of cellular double-stranded RNA (dsRNA), thereby preventing erroneous cytosolic MDA5-mediated dsRNA sensing. Mice lacking RNA editing by ADAR1 experience embryonic lethality but can live their full lifespan upon removal of MDA5. In humans, loss-of-function mutations in ADAR1 and gain-of-function mutations in MDA5 result in rare autoimmune diseases. Our recent work, through human genetics studies, reveals that RNA editing underlies genetic risk of common autoimmune and immune-related diseases. This well-established ADAR1-dsRNA-MDA5 axis serves as the foundation for therapeutic development in the treatment of cancer and autoinflammatory diseases.
This seminar is partially sponsored by NIH
Division(s): Division of Immunology and Molecular Medicine
https://events.berkeley.edu/mcb/event/243473-rna-editing-innate-immunity-and-autoinflammatory
Structural & Quantitative Biology Seminar, April 1/live/events/232513-structural-quantitative-biology-seminar

Structural & Quantitative Biology Seminar

/live/events/232513-structural-quantitative-biology-seminar
Divisions of Biochemistry, Biophysics and Structural Biology, Division of Cell Biology, Development and Physiology, and Genetics, Genomics, Evolution and Development Seminar, April 3https://events.berkeley.edu/mcb/event/208547-divisions-of-biochemistry-biophysics-andDivisions of Biochemistry, Biophysics & Structural Biology, Division of Cell Biology, Development & Physiology, and Genetics, Genomics, Evolution & Development Seminar
Division(s): Divisions of Biochemistry, Biophysics & Structural Biology, Division of Cell Biology, Development & Physiology, and Genetics, Genomics, Evolution & Development
https://events.berkeley.edu/mcb/event/208547-divisions-of-biochemistry-biophysics-and
MTx Seminar, April 4https://events.berkeley.edu/mcb/event/224087-mtx-seminarMTx Seminar
Division(s): MTx (Molecular Therapeutics)
https://events.berkeley.edu/mcb/event/224087-mtx-seminar
Division of Neurobiology and H. Wills Neuroscience Institute Seminar, April 4https://events.berkeley.edu/mcb/event/209802-division-of-neurobiology-and-h-wills-neuroscienceThis seminar is partially sponsored by NIH
Division(s): Division of Neurobiology & H. Wills Neuroscience Institute
https://events.berkeley.edu/mcb/event/209802-division-of-neurobiology-and-h-wills-neuroscience
Structural & Quantitative Biology Seminar, April 8/live/events/232524-structural-quantitative-biology-seminar

Structural & Quantitative Biology Seminar

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Division of Immunology and Molecular Medicine Seminar, April 9https://events.berkeley.edu/mcb/event/209032-division-of-immunology-and-molecular-medicineThis seminar is partially sponsored by NIH
Division(s): Division of Immunology and Molecular Medicine
https://events.berkeley.edu/mcb/event/209032-division-of-immunology-and-molecular-medicine
Division of Neurobiology and H. Wills Neuroscience Institute Seminar, April 11https://events.berkeley.edu/mcb/event/209801-division-of-neurobiology-and-h-wills-neuroscienceThis seminar is partially sponsored by NIH
Division(s): Division of Neurobiology & H. Wills Neuroscience Institute
https://events.berkeley.edu/mcb/event/209801-division-of-neurobiology-and-h-wills-neuroscience
Marian E. Koshland Memorial Lecture, April 12https://events.berkeley.edu/mcb/event/235027-marian-e-koshland-memorial-lectureMarian E. Koshland Memorial Lecture
Division(s): Marian E. Koshland Memorial Lecture Series
https://events.berkeley.edu/mcb/event/235027-marian-e-koshland-memorial-lecture
Structural & Quantitative Biology Seminar, April 15/live/events/206994-structural-quantitative-biology-seminar

Structural & Quantitative Biology Seminar

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Division of Immunology and Molecular Medicine Seminar, April 16https://events.berkeley.edu/mcb/event/209031-division-of-immunology-and-molecular-medicineThis seminar is partially sponsored by NIH
Division(s): Division of Immunology and Molecular Medicine
https://events.berkeley.edu/mcb/event/209031-division-of-immunology-and-molecular-medicine
Division of Neurobiology and H. Wills Neuroscience Institute Seminar, April 19https://events.berkeley.edu/mcb/event/222297-division-of-neurobiology-and-h-wills-neuroscienceThis seminar is partially sponsored by NIH
Division(s): Division of Neurobiology & H. Wills Neuroscience Institute
https://events.berkeley.edu/mcb/event/222297-division-of-neurobiology-and-h-wills-neuroscience
Cynthia A. Chan Memorial Lecture, April 22/live/events/224072-cynthia-a-chan-memorial-lecture

Cynthia A. Chan Memorial Lecture

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Towards a pan-sarbeovirus vaccine to protect against SARS-CoV-2 variants and animal sarbecoviruses without updating, April 24https://events.berkeley.edu/mcb/event/209030-alber-memorial-lecture-seminarDespite successful COVID-19 vaccines, there is an urgent need to combat future SARS-CoV-2 variants and spillovers of SARS-like betacoronaviruses (sarbecoviruses) threatening global health. We designed mosaic-8 protein nanoparticles that present randomly arranged sarbecovirus spike receptor-binding domains (RBDs) to elicit antibodies against epitopes that are conserved and relatively occluded rather than variable, immunodominant, and exposed. Epitope mapping by deep mutational scanning demonstrated increased targeting of conserved epitopes after mosaic-8 immunization. Our results suggest that vaccination with mosaic-8 RBD nanoparticles could protect against SARS-CoV-2 variants and future sarbecovirus spillovers.
Division(s): Alber Memorial Lecture
https://events.berkeley.edu/mcb/event/209030-alber-memorial-lecture-seminar
Neuroscience Student Seminar Series Seminar, April 25https://events.berkeley.edu/mcb/event/209800-neuroscience-student-seminar-series-seminarDivision(s): Neuroscience Student Seminar Serieshttps://events.berkeley.edu/mcb/event/209800-neuroscience-student-seminar-series-seminarStructural & Quantitative Biology Seminar, April 29/live/events/209985-structural-quantitative-biology-seminar

Structural & Quantitative Biology Seminar

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Division of Immunology and Molecular Medicine Seminar, April 30https://events.berkeley.edu/mcb/event/209029-division-of-immunology-and-molecular-medicineThis seminar is partially sponsored by NIH
Division(s): Division of Immunology and Molecular Medicine
https://events.berkeley.edu/mcb/event/209029-division-of-immunology-and-molecular-medicine
Department of Molecular and Cell Biology Annual Alumni Seminar, May 1https://events.berkeley.edu/mcb/event/232551-department-of-molecular-and-cell-biology-annualDepartment of Molecular & Cell Biology Annual Alumni Seminar
Division(s): Department of Molecular & Cell Biology
https://events.berkeley.edu/mcb/event/232551-department-of-molecular-and-cell-biology-annual
Marian E. Koshland Memorial Lecture, May 1https://events.berkeley.edu/mcb/event/235031-marian-e-koshland-memorial-lectureMarian E. Koshland Memorial Lecture
Division(s): Marian E. Koshland Memorial Lecture Series
https://events.berkeley.edu/mcb/event/235031-marian-e-koshland-memorial-lecture
MTx Seminar, May 2https://events.berkeley.edu/mcb/event/224086-mtx-seminarMTx Seminar
Division(s): MTx (Molecular Therapeutics)
https://events.berkeley.edu/mcb/event/224086-mtx-seminar
Neuroscience Student Seminar Series Seminar, May 2https://events.berkeley.edu/mcb/event/209799-neuroscience-student-seminar-series-seminarDivision(s): Neuroscience Student Seminar Serieshttps://events.berkeley.edu/mcb/event/209799-neuroscience-student-seminar-series-seminarMarian E. Koshland Memorial Lecture, May 3https://events.berkeley.edu/mcb/event/235030-marian-e-koshland-memorial-lectureMarian E. Koshland Memorial Lecture
Division(s): Marian E. Koshland Memorial Lecture Series
https://events.berkeley.edu/mcb/event/235030-marian-e-koshland-memorial-lecture
Division of Immunology and Molecular Medicine Seminar, May 14https://events.berkeley.edu/mcb/event/209028-division-of-immunology-and-molecular-medicineThis seminar is partially sponsored by NIH
Division(s): Division of Immunology and Molecular Medicine
https://events.berkeley.edu/mcb/event/209028-division-of-immunology-and-molecular-medicine
Divisions of Biochemistry, Biophysics and Structural Biology, Division of Cell Biology, Development and Physiology, and Genetics, Genomics, Evolution and Development, May 15https://events.berkeley.edu/mcb/event/208546-divisions-of-biochemistry-biophysics-andDivisions of Biochemistry, Biophysics & Structural Biology, Division of Cell Biology, Development & Physiology, and Genetics, Genomics, Evolution & Development
Division(s): Divisions of Biochemistry, Biophysics & Structural Biology, Division of Cell Biology, Development & Physiology, and Genetics, Genomics, Evolution & Development
https://events.berkeley.edu/mcb/event/208546-divisions-of-biochemistry-biophysics-and
Division of Neurobiology and H. Wills Neuroscience Institute Seminar, May 16https://events.berkeley.edu/mcb/event/209798-division-of-neurobiology-and-h-wills-neuroscienceThis seminar is partially sponsored by NIH
Division(s): Division of Neurobiology & H. Wills Neuroscience Institute
https://events.berkeley.edu/mcb/event/209798-division-of-neurobiology-and-h-wills-neuroscience
Divisions of Biochemistry, Biophysics and Structural Biology, Division of Cell Biology, Development and Physiology, and Genetics, Genomics, Evolution and Development Seminar, May 22https://events.berkeley.edu/mcb/event/208545-divisions-of-biochemistry-biophysics-andDivisions of Biochemistry, Biophysics & Structural Biology, Division of Cell Biology, Development & Physiology, and Genetics, Genomics, Evolution & Development Seminar
Division(s): Divisions of Biochemistry, Biophysics & Structural Biology, Division of Cell Biology, Development & Physiology, and Genetics, Genomics, Evolution & Development
https://events.berkeley.edu/mcb/event/208545-divisions-of-biochemistry-biophysics-and
Division of Neurobiology and H. Wills Neuroscience Institute Seminar, May 23https://events.berkeley.edu/mcb/event/209797-division-of-neurobiology-and-h-wills-neuroscienceThis seminar is partially sponsored by NIH
Division(s): Division of Neurobiology & H. Wills Neuroscience Institute
https://events.berkeley.edu/mcb/event/209797-division-of-neurobiology-and-h-wills-neuroscience
Division of Immunology and Molecular Medicine Seminar, Nov. 5https://events.berkeley.edu/mcb/event/223659-division-of-immunology-and-molecular-medicineThis seminar is partially sponsored by NIH
Division(s): Division of Immunology and Molecular Medicine
https://events.berkeley.edu/mcb/event/223659-division-of-immunology-and-molecular-medicine