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Monday, April 16, 2018

A Tale of Two Strains: Ocular Studies in B6 and BALB/c Mice

Seminar: Oxyopia Seminar | April 16 | 12-1 p.m. | 489 Minor Hall

Elizabeth Berger, PhD, Professor, Wayne State University

Neuroscience Institute, Helen Wills

Abstract: Corneal infection with Pseudomonas aeruginosa perforates the cornea in C57BL/6 (B6), but not BALB/c mice. Comparative analysis of these two responses has revealed that B6 mice, type 1-dominant responders, exhibit increased inflammation, leading to an exacerbated disease response when compared to BALB/c mice, which demonstrate a less severe/resistant response and are classified as type...   More >

Tuesday, April 17, 2018

Cognitive Neuroscience Colloquium: Neural oscillations: What we're doing wrong

Colloquium | April 17 | 3:30-5 p.m. | 5101 Tolman Hall

Brad Voytek, Professor, Department of Cognitive Science, UCSD

Department of Psychology

Friday, April 20, 2018

Optogenetic and Chemogenetic Tools for Mapping Molecular and Cellular Circuits: Nano Seminar Series

Seminar | April 20 | 2-3 p.m. | 60 Evans Hall

Prof. Alice Ting, Stanford University, Genetics/Biology/Chemistry

Berkeley Nanosciences and Nanoengineering Institute

The first part of the talk will describe optogenetic tools we have developed for labeling and manipulating functional circuits in the brain (e.g., FLARE and related tools).

The second part of the talk will describe chemogenetic tools we have developed for mapping molecular interactions in living cells (e.g., APEX and TurboID).

Alice Ting did her PhD in Chem here at UC Berkeley...   More >

Monday, April 23, 2018

Mobilizing Synaptic Plasticity to Promote Recovery from Amblyopia

Seminar: Oxyopia Seminar | April 23 | 12-1 p.m. | 489 Minor Hall

Dr. Mark Bear, PhD, PiCower Professor of Neuroscience, MIT

Neuroscience Institute, Helen Wills

Amblyopia is a prevalent form of visual disability that arises during infancy and early childhood when inputs to the visual cortex from the two eyes are poorly balanced (e.g., by misalignment of the eyes, asymmetric refraction, or opacities and obstructions of one eye). Characteristics of amblyopia are very poor acuity in one eye, and an attendant loss of stereopsis. The current standard of care...   More >

Tuesday, April 24, 2018

Thursday, April 26, 2018

Deciphering the Dynamics of the Unconscious Brain Under General Anesthesia

Seminar | April 26 | 3:30-4:30 p.m. | 101 Life Sciences Addition

Emery Brown , Massachusetts Institute of Technology

Department of Molecular and Cell Biology

This seminar is partially sponsored by NIH

Friday, April 27, 2018

Education, plasticity and learning: the virtuous cycle between education and neuroscience

Lecture | April 27 | 12-1:30 p.m. | 3105 Tolman Hall

Jason D. Yeatman, PhD, Department of Speech & Hearing Sciences, University of Washington

Department of Psychology

Reading instruction prompts the emergence of neural circuits that are specialized for rapidly translating printed symbols into sound and meaning. Understanding how these circuits differ in children with dyslexia, and change with learning, is an important scientific challenge that holds practical implications for education. In this talk I will present new data linking changes in the white matter...   More >

Thursday, May 3, 2018

Perturbation and Control of Human Brain Network Dynamics

Seminar | May 3 | 3:30-4:30 p.m. | 101 Life Sciences Addition

Dani Bassett, University of Pennsylvania

Neuroscience Institute, Helen Wills

Abstract: The human brain is a complex organ characterized by heterogeneous patterns of interconnections. New non-invasive imaging techniques now allow for these patterns to be carefully and comprehensively mapped in individual humans, paving the way for a better understanding of how wiring supports our thought processes. While a large body of work now focuses on descriptive statistics to...   More >

Monday, May 7, 2018

Oxyopia - Graduate Student Seminar

Seminar: Oxyopia Seminar | May 7 | 12-1:30 p.m. | 489 Minor Hall

Paul Cullen, John Flanagan Lab; Brian Cheung, Bruno Olshausen Lab

Neuroscience Institute, Helen Wills

Paul Cullen
John Flanagan Lab
Title: The Secret Lives of Retinal Astrocytes
Abstract: The study of glia – the support cells of the central nervous system – has come a long way since Rudolf Virchow described a connective tissue of the brain that he termed ‘nervenkitt’ in 1856. Rather than a passive scaffolding for neurons (the word ‘glia’ means glue in Greek), these cells are responsible for a...   More >

Tuesday, May 22, 2018

Expander graph architectures for high-capacity neural memory

Seminar: Redwood Seminar | May 22 | 12-1:30 p.m. | 560 Evans Hall

Rishidev Chaudhuri, UT Austin/Simons Institute UC Berkeley

Neuroscience Institute, Helen Wills

Memory networks in the brain must balance two competing demands. On the one hand, they should have high capacity to store the large numbers of stimuli an organism must remember over a lifetime. On the other hand, noise is ubiquitous in the brain and memory is typically retrieved from incomplete input. Thus, memories must be encoded with some redundancy, which reduces capacity. Current neural...   More >

Wednesday, May 23, 2018

Characterizing neurons in the visual area V4 through interpretable machine learning

Seminar: Redwood Seminar | May 23 | 12-1:30 p.m. | 560 Evans Hall

Reza Abbasi-Asl, UC Berekely

Neuroscience Institute, Helen Wills

In the past decade, research in machine learning has been exceedingly focused on the development of algorithms and models with remarkably high predictive capabilities. Models such as convolutional neural networks (CNNs) have achieved state-of-the-art predictive performance for many tasks in computer vision, autonomous driving, and transfer learning in areas such as computational neuroscience....   More >

Thursday, May 24, 2018

Wednesday, May 30, 2018

Inference and Efficient Coding in Natural Auditory Scenes

Seminar: Redwood Seminar | May 30 | 12-1:30 p.m. | 560 Evans Hall

Wiktor Mlynarski, MIT

Neuroscience Institute, Helen Wills

Processing of natural stimuli in sensory systems has been traditionally studied within two theoretical frameworks: probabilistic inference and efficient coding. Probabilistic inference specifies optimal strategies for learning about relevant properties of the environment from local and ambiguous sensory signals. Efficient coding provides a normative approach to study encoding of natural stimuli...   More >

Thursday, June 14, 2018

Eavesdropping on Cortical Plasticity

Seminar: Neuroscience Seminar | June 14 | 3:30-4:30 p.m. | 125 Li Ka Shing Center

Adi Mizrahi, The Edmond and Lily Safra Center for Brain Sciences, The Hebrew University of Jerusalem

Neuroscience Institute, Helen Wills

One of the overarching goal in our lab is to understand cortical plasticity in adult circuits. This goal remains challenging because cortical neurons are functionally heterogeneous and access to specific active neurons for further experimentation is limited. In the primary auditory cortex (A1), for example, spiking responses to natural stimuli like vocalization cannot be easily predicted from...   More >

Wednesday, June 20, 2018

Optimal sensors in random environments

Seminar: Redwood Seminar | June 20 | 12-1:30 p.m. | 560 Evans Hall

Sarah Marzen, MIT

Neuroscience Institute, Helen Wills

The efficient coding hypothesis has revolutionized theoretical neuroscience. I would argue that it is best understood using rate-distortion theory. I use rate-distortion theory to inspire a simple model of sensory adaptation. In randomly drawn, fluctuating environments, this model suggests that neurogenesis in sensory regions is unnecessary and predicts that biological sensors are poised to just...   More >

Monday, June 25, 2018

Expression of ethanol sensitive glycine receptors in several brain regions

Seminar: Neuroscience Seminar | June 25 | 2-3:30 p.m. | 125 Li Ka Shing Center

Luis Aguayo, University of Concepcion, Chile

Neuroscience Institute, Helen Wills

Synaptic glycine receptors (GlyR) are expressed primarily in spinal cord and brain stem neurons. GlyRs are sensitive to general anesthetics, neurosteroids, Zn2+ and ethanol. Recently, GlyRs were also found in other supratentorial regions, but their properties are largely unknown. Mesolimbic regions, such as ventral tegmental area (VTA) and nucleus accumbens (nAc), were also found to express GlyRs...   More >

Thursday, August 30, 2018

The Ins and Outs of Visual cortex

Seminar | August 30 | 3:30-4:30 p.m. | 101 Life Sciences Addition

Massimo Scanziani, University of California San Francisco, Center for Integrative Neuroscience Sandler Neurosciences Center

Department of Molecular and Cell Biology

This seminar is partially sponsored by NIH

Monday, September 10, 2018

An objective functional biomarker of retinal ganglion cell function: Applications for probing disease mechanisms

Seminar: Oxyopia Seminar | September 10 | 11:10 a.m.-12:30 p.m. | 489 Minor Hall

Suresh Viswanathan, Associate Professor & Chair of Biological and Vision Sciences, SUNY College of Optometry

Neuroscience Institute, Helen Wills

Work over the last decade and a half have identified and characterized a retinal ganglion cell nerve component in the flash electroretinogram. This talk will review the evidence for retinal ganglion cell origin of this potential, its mechanism of generation and applications towards understanding the pathophysiological mechanisms of glaucoma and mild traumatic brain injury.

Wednesday, September 12, 2018

Correlated neural activity across the brains of socially interacting bats

Seminar: Redwood Seminar | September 12 | 12-1 p.m. | 560 Evans Hall

Wujie Zhang, Yartsev Lab, UC Berkeley

Neuroscience Institute, Helen Wills

Social interaction is fundamental to our everyday life and that of diverse animals. When two animals interact, they behave in different ways. Thus, to get a full picture of the neural activity underlying each interaction, we need to record from the brains of both animals at the same time. We do so in a highly social mammal, the Egyptian fruit bat, using wireless electrophysiology, which allows...   More >

Monday, September 17, 2018

​Graduate Students Seminar

Seminar: Oxyopia Seminar | September 17 | 11:10 a.m.-12:30 p.m. | 489 Minor Hall

Vivek Labhishetty, PhD; Baladitya Yellapragada, PhD

Neuroscience Institute, Helen Wills

Vivek Labhishetty's Abstract
Retinal-Conjugate Surfaces: The Blur Horopter
When we fixate at an object, the image of that object is brought to sharp focus on the fovea due to the eye’s accommodation. Other objects in the periphery may be farther or nearer than best focus on those parts of the retina. We measured the shape of surface of best focus in the world as the eye accommodates to...   More >

Information decomposition

Seminar: Redwood Seminar | September 17 | 12-1 p.m. | 560 Evans Hall

Juergen Jost, MPI for Mathematics in the Sciences, Leipzig

Neuroscience Institute, Helen Wills

In many situations, two or more sources have some information about a target. For instance, sensory input and context information can jointly determine the firing pattern of a neuron. Since the information from the two sources is typically not identical, one wishes to decompose it in those parts that are unique to each source, what is shared between them and what is complementary, that is,...   More >

Tuesday, September 18, 2018

Learning Representations for Planning

Seminar: Redwood Seminar | September 18 | 12-1 p.m. | 560 Evans Hall

Aviv Tamar, Postdoc, UC Berkeley's Artificial Intelligence Research Lab

Neuroscience Institute, Helen Wills

How can we build autonomous robots that operate in unstructured and dynamic environments such as homes or hospitals?
This problem has been investigated under several disciplines, including planning (motion planning, task planning, etc.), and reinforcement learning. While both of these fields have witnessed tremendous progress, each have fundamental drawbacks when it comes to...   More >

Wednesday, September 19, 2018

Thursday, September 20, 2018

Monday, September 24, 2018

​Graduate Student Seminar

Seminar: Oxyopia Seminar | September 24 | 11:10 a.m.-12:30 p.m. | 489 Minor Hall

Ethan Bensinger, Roorda Lab; Baladitya Yellapragada, Yu Lab

Neuroscience Institute, Helen Wills

Ethan Bensinger's Talk Title
Dysflective Cones: Differences in Cone Reflectivity and Function in Healthy Subjects
Confocal Adaptive Optics Scanning Laser Ophthalmoscope (AOSLO) images acquired in healthy subjects reveal small areas with diminished cone reflectivity. In a survey of AOSLO images these transient hyporeflective areas of cones were found in 19 of the 80 eyes. 3 healthy subjects with...   More >

The neural circuits underlying motor planning and short-term memory

Seminar | September 24 | 12-1 p.m. | 125 Li Ka Shing Center

Karel Svoboda, Janelia Research Campus, HHMI

Neuroscience Institute, Helen Wills

Our goal is to uncover the principles by which mammalian neural circuits perform fundamental computations, from perception to action. Cortex is parcellated into areas with distinct functions, each of which contains complex local circuits. Cortical areas in turn associate into mesoscale circuits with other cortical and subcortical areas via long-range connections. Information is represented by...   More >

Wednesday, September 26, 2018

A New Benchmark and Progress Toward Improved Weakly Supervised Learning

Seminar: Redwood Seminar | September 26 | 12-1 p.m. | 560 Evans Hall

Russ Webb, Apple

Neuroscience Institute, Helen Wills

A primary goal of this work is to give a clear example of the limits of current, deep-learning techniques and suggest how progress can be made. The presentation will include a discussion of open questions, unpublished experiments, suggestions on how to make progress. This work is founded on the paper Knowledge Matters: Importance of Prior Information for Optimization by Gulcehre et. al., which...   More >

Friday, September 28, 2018

Monday, October 1, 2018

(Computer) Vision without Sight: Finding, Reading, and Magnifying Text

Seminar: Oxyopia Seminar | October 1 | 11:10 a.m.-12:30 p.m. | 489 Minor Hall

Roberto Manduchi, Professor of Computer Engineering, UC Santa Cruz

Neuroscience Institute, Helen Wills

Reading is a pervasive activity in our daily life. We read text printed on books and documents, shown on directional signs and advertisement, and displayed on computer and smartphone screens. People who are blind can read text using OCR on their smartphone; those with low vision may magnify onscreen content. But these tasks are not always easy. Reading a document with OCR requires taking a...   More >

Thursday, October 11, 2018

Wednesday, October 17, 2018

Berkeley ACM A.M. Turing Laureate Lecture: Towards a Conscious AI: A Computer Architecture Inspired by Neuroscience

Colloquium | October 17 | 4-5 p.m. | Sutardja Dai Hall, Banatao Auditorium

Manuel Blum, UC Berkeley

Electrical Engineering and Computer Sciences (EECS)

Thanks to major advances in neuroscience, we are on the brink of a scientific understanding of how the brain achieves consciousness. This talk will describe neuroscientist Bernard Baars' Global Workspace Model (GWM) of the brain, its implications for understanding consciousness, and a novel computer architecture that it inspires. The Model gives insight for the design of machines that truly...   More >

Thursday, October 18, 2018

Division of Neurobiology and H. Wills Neuroscience Institute

Seminar | October 18 | 3:30-4:30 p.m. | 101 Life Sciences Addition

Adam Kepecs

Department of Molecular and Cell Biology

This seminar is partially sponsored by NIH

Thursday, November 1, 2018

Information Storage in Memory Engrams

Seminar | November 1 | 3:30-4:30 p.m. | 101 Life Sciences Addition

Tomas Ryan, Trinity College Dublin, School of Biochemistry and Immunology,

Department of Molecular and Cell Biology

This seminar is partially sponsored by NIH

Friday, November 9, 2018

Attentional Episodes and Cognitive Control

Seminar: Neuroscience Seminar | November 9 | 11 a.m.-12:30 p.m. | 1104 Berkeley Way West

John Duncan, MRC Cognition & Brain Sciences Unit, Cambridge

Neuroscience Institute, Helen Wills

Abstract: Human fMRI studies show a tightly-localised set of “multiple-demand” or MD regions, involved in solution of many different cognitive challenges, widely separated yet strongly functionally connected, and linked to standard measures of fluid intelligence. Multiple-demand regions are generally associated with “cognitive control”, but how should control be conceived? Using data from...   More >

Tuesday, November 27, 2018

Division of Immunology and Pathogenesis

Seminar | November 27 | 11 a.m.-12 p.m. | 101 Life Sciences Addition

Jun R. Huh, Harvard University

Department of Molecular and Cell Biology

This seminar is partially sponsored by NIH

Wednesday, November 28, 2018

Thursday, November 29, 2018

Convergent circuitry for thermoregulation

Seminar | November 29 | 3:30-4:30 p.m. | 101 Life Sciences Addition

Lily Jan, University of California, San Francisco

Department of Molecular and Cell Biology

This seminar is partially sponsored by NIH

Thursday, December 6, 2018

Division of Neurobiology and H.Wills Neuroscience Institute

Seminar | December 6 | 3:30-4:30 p.m. | 101 Life Sciences Addition

James Trimmer, University of California, Davis, Department of Pharmacology

Department of Molecular and Cell Biology

This seminar is partially sponsored by NIH