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BioE Seminar: “Physical Phenotyping”

Seminar: BioE Seminars: Seminars of interest | March 15 | 12-1 p.m. |  Sibley Auditorium, Bechtel Engineering Center

Dino Di Carlo, UCLA

Bioengineering (BioE)

Spring 2017 Seminar Series

Wednesday, March 15
12noon - 1:00pm
Bechtel Engineering Center – Sibley Auditorium

Dino Di Carlo
Professor of Bioengineering

“Physical Phenotyping”

My lab uses microtechnology to interface at the scale of biology to aid in scientific investigation, develop new approaches to diagnose and monitor disease, and engineer therapies. A part of our laboratory develops tools to assay and exploit physical properties of cells in diagnostics and drug screening. Physical properties of cells can provide integrative, rapid, and low-cost information about disease. My discussion will focus on instruments we have developed that quantify single-cell physical phenotypes such as deformability, size, and contractility. These new tools show promise to enable diagnostic and screening approaches that assay immune cell function at the point-of-care, tumor cell malignancy with higher confidence than molecular markers alone, and many other cell fate decisions associated with disease.