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<< Monday, April 16, 2018 >>

Monday, April 16, 2018

A Tale of Two Strains: Ocular Studies in B6 and BALB/c Mice

Seminar: Oxyopia Seminar | April 16 | 12-1 p.m. | 489 Minor Hall

Elizabeth Berger, PhD, Professor, Wayne State University

Neuroscience Institute, Helen Wills

Abstract: Corneal infection with Pseudomonas aeruginosa perforates the cornea in C57BL/6 (B6), but not BALB/c mice. Comparative analysis of these two responses has revealed that B6 mice, type 1-dominant responders, exhibit increased inflammation, leading to an exacerbated disease response when compared to BALB/c mice, which demonstrate a less severe/resistant response and are classified as type...   More >