Vision to Action: Towards a Cellular-Resolution Atlas of the Zebrafish Visual and Visuomotor System
Seminar | October 29 | 4-5 p.m. | 125 Li Ka Shing Center
Herwig Baier, Department Genes – Circuits – Behavior, Max Planck Institute of Neurobiology, 82152 Martinsried, Germany
Understanding brain-wide neuronal dynamics and behavior requires a detailed map of the underlying circuit architecture. We built an interactive cellular-resolution atlas of the zebrafish brain, with a focus on the visual and visuomotor system, and generated from our dataset an inter-areal wiring diagram, which serves as ground truth for synapse-scale, electron microscopic reconstructions. We have used this resource to guide optogenetic interrogations of functional inputs and outputs of the tectum, a core sensorimotor processing hub of the vertebrate brain.