Focused Ultrasound Neuromodulation

Seminar | April 18 | 12-1 p.m. | 106 Stanley Hall

 Kim Butts Pauly, Stanford University

 Bioengineering (BioE)

Ultrasound can be focused to achieve high intensities deep in the brain. It is currently FDA approved for the treatment of essential tremor, which affects 4% of the US population age 40 and over. This talk will discuss MRI-guided focused ultrasound technology for this application, as well as ongoing research in this area. At low intensities, there is evidence that ultrasound acts on mechanosensitive ion channels to stimulate neurons. The potential here is the non-invasive modulation of deep brain structures. This talk will discuss the evidence for ultrasound-based neuromodulation at a variety of scales from the retina, to the mouse, to humans.