Amgen Seminar in Organic Chemistry: How structure can inform GPCR drug discovery

Seminar | February 19 | 11 a.m.-12 p.m. | 120 Latimer Hall | Canceled

 Bryan Roth, Department of Pharmacology, UNC School of Medicine

 College of Chemistry

In this talk I will first present unpublished work highlighting our current structure-based efforts to understand how small molecules interact with G protein coupled receptors (GPCRs). I will then show how these structural insights can facilitate GPCR drug discovery.

Recent papers: Wang et al, Science 2017 (PMID: 29051383); Wang et al, Nature 2018 (PMID: 29466326); Che et al, Cell 2018 (PMID: 29307491)

 Light refreshments will be served at 10:50 at The Coffee Lab, 510-643-0572