Total Synthesis of Neurologically Active Terpenoid Natural Products

Seminar | February 27 | 11 a.m.-12 p.m. | 120 Latimer Hall

 Prof. Tim Newhouse, Department of Chemistry, Yale University

 College of Chemistry

This talk will describe the total synthesis of neurologically active terpenoid natural products using novel strategies and methodologies for step-efficient syntheses. Methodological developments in the area of allyl-palladium catalysis will be described in detail that have allowed for alpha,beta-dehydrogenation of a variety of carbonyl compounds. Unique strategies and key retrosynthetic disconnections are guided by computational investigation.

 Light refreshments will be served at 10:50 at The Coffee Lab, 510-643-0572